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Evidence

Moderate evidence

Common protocol200–900 mg/day cocoa flavanols across trials——

Protocols mapped

1 goal-specific

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Timing

With or without food; account for caffeine and theobromine

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Expected effect

Study-specific; commonly several weeks

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Primary uses

Vascular-function researchBlood-pressure researchCocoa polyphenols

Watch for

Headache · Digestive upset

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