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Put up to three ingredients next to each other. See where the evidence, dosing, timing, and tradeoffs differ.

Supplement 1Supplement 2Supplement 3

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Evidence

Moderate evidence

Common protocol2–3 g leucine within a protein-containing meal——

Protocols mapped

1 goal-specific

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Timing

With protein-containing meals

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Expected effect

Study-specific; commonly several weeks

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Primary uses

Muscle protein synthesisProtein-quality supportOlder-adult research

Watch for

Gastrointestinal discomfort is possible · Long-term safety data may be limited

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