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Compare supplements

Put up to three ingredients next to each other. See where the evidence, dosing, timing, and tradeoffs differ.

Measure
SAMeSAMe
Add a supplement
Add a supplement
Evidence
Moderate evidence
Common protocol400–1,600 mg/day across clinical trials——
Protocols mapped

1 goal-specific

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Timing

Morning, often divided

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Expected effect

Study-specific; commonly several weeks

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Primary uses
Depression researchOsteoarthritis researchMethylation
Watch for

Nausea · Anxiety

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