General Health · Ingredient guide

Omega-3

EPA and DHA fatty acids found in fish and algae oils with established roles in cardiovascular biology.

Compare
Evidence strengthStrong evidence
Based on consistency, quality and relevance of human research—not podcast mentions.
Common research protocol1–2 g combined EPA + DHA daily
Protocols mapped2 goal-specific protocols
Evidence reviewed throughSeptember 2026
Evidence verdict

Strong for lowering elevated triglycerides at prescription-level doses. General prevention, mood and cognition claims are more context-dependent.

Scientific evidence2 reviewed sourcesDetermines the evidence grade
Expert & media context1 reviewed sourceDoes not change the grade alone
Biohacking / experimental1–3 g/day EPA discussed in brain and mood contexts

Context-specific · See what the evidence gap means.

Open experimental view →
01

What it is & primary uses

EPA and DHA fatty acids found in fish and algae oils with established roles in cardiovascular biology.

Triglyceride supportGeneral cardiovascular health
02

Main benefits

  • Supports healthy triglyceride levels
  • Provides EPA and DHA when dietary intake is low
03

Studied protocols

Research doses are grouped by outcome. They describe study designs—not a personal prescription.

Correct low dietary EPA + DHA intake

~1–2 g/day combined EPA + DHA

Moderate confidence
Study duration
Long term with food
Interpretation
A nutrition-support range, not a proven treatment dose for every healthy adult.
Hypertriglyceridemia treatment

4 g/day prescription omega-3

High confidence
Study duration
Clinician-supervised
Interpretation
A medical treatment context; over-the-counter fish-oil labels are not interchangeable with prescription products.

Clinical or experimental context—professional guidance is especially appropriate.

04Food sources & equivalents
Food sources & equivalents

Can food provide a studied amount?

Practical food match
Comparison target~1–2 g/day combined EPA + DHA nutrition-support range

Fatty fish can supply EPA and DHA in quantities comparable with the app's nutrition-support range.

Farmed Atlantic salmon, cooked~46–93 g

Approximately 1–2 g EPA + DHA based on 1.83 g per 85 g

Atlantic herring, cooked~50–99 g

Approximately 1–2 g EPA + DHA based on 1.71 g per 85 g

How this was estimated
Food weight scales from the NIH table's EPA plus DHA per 3 oz (85 g) serving.
Important limitation
EPA and DHA vary by species, origin and feed. Plant ALA from flax or walnuts is not dose-equivalent because conversion to EPA and DHA is limited.

Food equivalents compare ingredient mass using published composition values. They do not prove equal absorption, formulation, physiological effect, safety or personal need.

Source: NIH ODS: EPA and DHA content of selected foods ↗
05How to take it for absorption & tolerance
Meal relationship

With dietary fat

Evidence-informed
Take EPA and DHA with a meal that contains fat.

Fat stimulates digestion and absorption of lipid-based products; fish-oil bioavailability is higher with a fat-containing meal than in a fasted state.

Practical approach
Take the serving with a main meal and compare products by combined EPA plus DHA.
Watch for
Splitting the dose across meals can reduce fishy aftertaste or reflux.

Meal guidance reflects human pharmacokinetic, clinical, official-label or evidence-review sources where available. A food pairing can change absorption or tolerability, but does not make a supplement necessary, effective or safe for every person.

Source: Absorption of fish-oil fatty acids with meals ↗
06Supplement interaction check
Library interaction context156 ingredients · 0 mapped signals for this guide

An unlisted pair means no established pair-specific interaction was identified in this review—not proof that every dose, product or person is safe.

No pair-specific signal listedNo established interaction with another Dose Radar ingredient was identified in this review.

This is not proof that every dose, product or user context is safe. Medication and condition checks still apply.

07Research notes
Evidence verdict

Strong for lowering elevated triglycerides at prescription-level doses. General prevention, mood and cognition claims are more context-dependent.

Compare products by combined EPA and DHA, not total fish-oil weight.

TimingWith a fat-containing meal
Time to expected effectWeeks to months
08Scientific references
09Expert & media references
Context sourceUsed to understand what professionals discuss

Podcast and practitioner statements are clearly separated from research. They may explain practice or emerging ideas, but do not prove efficacy.